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Synthesis of some new 2 aryl 3 [(4 methyl cinnamoyl) amino] 5 methyl 4 oxothiazolidines and evaluation for their antimicrobial activity

Author:P. M.Chatrabhuji, K.S.Nimavat, K.B.Vyas and N. K.Undavia

Abstract:
4-Oxothiazolidines(1a-o) have been synthesized by cyclisation of various Schiff bases with thiolactic acid. The schiff bases are obtained by the condensation reaction of 4-methyl cinnamoyl hydrazine with different benzaldehydes. The synthesized compounds are identified on the basis of spectral and elemental analysis. All the products have been evaluated for their in vitro antimicrobial activity against various strains of bacteria.